姓名：邢永政

性别：男

职称：研究员

邮箱：y.xing@sdu.edu.cn

地址：山东省济南市历城区山大南路27号山东大学中心校区

学习与工作经历：

2023年7月-至今 山东大学国家胶体材料工程技术研究中心，研究员

2016年1月-2023年6月 英国伦敦大学学院化学系，博士后

2012年11月-2015年12月 德国慕尼黑大学物理系，博士后

2007年9月-2012年10月 清华大学化学系 & 中科院国家纳米科学中心，博士

2003年9月-2007年7月 山东大学生命科学学院，学士

研究方向：

1.先进纳米传感器件的精准构建与开发

2.核酸及功能高分子自组装体系与功能化

3.智能纳米材料的精准设计、制备与应用

已发表论文列表：(*—通讯作者)

1.B.Yang*, T. Cui, L. Guo, L. Dong, J. Wu,Y. Xing*, Y. Xu, J. Chen, Y. Wang, Z. Cui, Y. Dong*. Advanced Smart Biomaterials for Regenerative Medicine and Drug Delivery Based on Phosphoramidite Chemistry: From Oligonucleotides to Precision Polymers.Biomacromolecules25, 2701–2714 (2024)

2.Y. Xing*, A. Dorey, S. Howorka*. Multi-Stimuli Responsive and Mechano-Actuated Biomimetic Membrane Nanopores Self-Assembled from DNA.Adv.Mater.35, e202300589 (2023)

3.S. Suh,Y. Xing, A. Rottensteiner, R. Zhu, Y. Oh, S. Howorka, P. Hinterdorfer. Molecular Recognition in Confined Space Elucidated with DNA Nanopores and Single-Molecule Force Microscopy.Nano Letters23, 10, 4439-4447 (2023)

4.Y. Xing*, A. Rottensteiner, J. Ciccone, S. Howorka*. Functional nanopores enabled with DNA.Angew. Chem. Int. Ed.62, e202303103 (2023)

5.Y. Xing, A. Dorey, L. Jayasinghe, S. Howorka.Highly Shape and Size Tunable Membrane Nanopores Made with DNA.Nature Nanotechnology17, 708-713 (2022)

6.S. Dey, A. Dorey, L. Abraham,Y. Xing, I. Zhang, F. Zhang, S. Howorka, H. Yan. A Reversibly Gated Protein-Transporting Membrane Channel Made of DNA.Nature Communications13, 2271 (2022)

7.C. Lanphere, D. Offenbartl-Stiegert, A. Dorey, G. Pugh, E. Georgiou,Y. Xing, J. Burns, S. Howorka. Design, assembly, and characterization of membrane-spanning DNA nanopores. Nature Protocols16, 86-130 (2021)

8.T. Diederichs, G. Pugh, A. Dorey,Y. Xing, J. Burns, Q. Nguyen, M. Tornow, R. Tampé, S. Howorka. Synthetic Protein-conductive Membrane Nanopores Built with DNA. Nature Communications10, 5018 (2019)

9.C. Li, X. Zhou, Y. Shao, P. Chen,Y. Xing, Z. Yang, Z. Li, D. Liu. A Supramolecular Hydrogel with Identical Cross-linking Point Density but Distinctive Rheological Properties.Mater. Chem. Front. 1, 654-659 (2017).

10.C. Li, A. Faulkner-Jones, A. Dun, J. Jin, P. Chen,Y. Xing, Z. Yang, Z. Li, W. Shu, D. Liu, R. Ducan. A Rapid-formed Supramolecular Polypeptide-DNA Hydrogel for in-situ Multi-layer 3D Bioprinting.Angew. Chem. Int. Ed.54, 3957-3961 (2015).

11.S. Kocabey, S. Kempter, J. List,Y. Xing, W. Bae, W. Shih, F. Simmel, T. Liedl. Membrane-Assisted Growth of DNA Origami Nanostructure Arrays.ACS Nano9, 3530-3539 (2015).

12.J. Jin,Y. Xing, Y. Xi, X. Liu, T. Zhou, X. Ma, Z. Yang, S. Wang, D. Liu. A Triggered DNA Hydrogel Cover to Envelop and Release Single Cells.Adv. Mater.25, 4714-4717 (2013).

13.C. Chen, M. Li,Y. Xing, Y. Li, C. Joedecke, J. Jin, Z. Yang, D. Liu. Study of pH-Induced Folding and Unfolding Kinetics of DNA i-Motif by Stopped-Flow Circular Dichroism.Langmuir28, 17743-17748 (2012).

14.Y. Yang, Y. Sun, Y. Yang,Y. Xing, T. Zhang, Z. Wang, Z. Yang, D. Liu. The Influence of Tetra (Ethylene Glycol) (EG4) Substitution at the Loop Region on Intramolecular DNAi-motif.Macromolecules45, 2643-2647 (2012).

15.T. Zhang, Y. Sun, P. Chen,Y. Xing, Z. Yang, L. Xu, D. Liu. A New Strategy Improves Assembly Efficiency of DNA Mono-modified Gold Nanoparticles.Chem. Comm.47, 5774-5776 (2011).

16.Y. Xing, Z. Yang, D. Liu. A Responsive Hidden Toehold to Enable Controllable DNA Strand Displacement Reaction.Angew. Chem. Int. Ed.50, 11934-11936 (2011).

17.Y. Xing, E. Cheng, Y. Yang, P. Chen, T. Zhang, Y. Sun, Z. Yang, D. Liu. Self-Assembled DNA Hydrogels with Designable Thermal and Enzymatic Responsiveness.Adv.Mater.23, 1117-1121 (2011).

18.E. Cheng,Y. Xing, P. Chen, Y. Yang, Y. Sun, D. Zhou, L. Xu, Q. Fan, D. Liu. A pH-Triggered, Fast-Responding DNA Hydrogel.Angew. Chem. Int. Ed.48, 7660-7663 (2009).